Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 15/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 13/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.62 |
| ▸ | VNN1 | O95497 | 3/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19710840 | 0.93 | VNN1 (0.61) | HDAC6HDAC3HDAC1HDAC2VNN1 | |
| SCHEMBL24967744 | 0.85 | VNN1 (0.56) | HDAC6HDAC3HDAC1HDAC2VNN1 | |
| SCHEMBL24967738 | 0.84 | HDAC6 (0.52) | HDAC6HDAC3HDAC1HDAC2VNN1 | |
| SCHEMBL28247582 | 0.83 | HDAC6 (0.60) | HDAC6HDAC3HDAC1HDAC2VNN1 | |
| SCHEMBL24968663 | 0.83 | HDAC3 (0.53) | HDAC6HDAC3HDAC1HDAC2VNN1 | |
| SCHEMBL28247610 | 0.80 | HDAC6 (0.61) | HDAC6HDAC3HDAC1HDAC2VNN1 | |
| SCHEMBL28248162 | 0.80 | HDAC6 (0.60) | HDAC6HDAC3HDAC1HDAC2VNN1 | |
| SCHEMBL28248252 | 0.79 | HDAC6 (0.52) | HDAC6HDAC3HDAC1HDAC2VNN1 | |
| SCHEMBL19710705 | 0.79 | HDAC6 (0.67) | HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL24968639 | 0.78 | HDAC6 (0.59) | HDAC6HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362445-B1 | OXADIAZOLE AMINE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2023-01-25 | — | — | EP | disclosed |