Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 18/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 18/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 18/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 18/20 | 0.53 |
| ▸ | VNN1 | O95497 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28865440 | 0.86 | HDAC6 (0.46) | HDAC3HDAC1HDAC2HDAC6VNN1 | |
| SCHEMBL24967738 | 0.83 | HDAC6 (0.52) | HDAC3HDAC1HDAC2HDAC6VNN1 | |
| SCHEMBL24968632 | 0.83 | HDAC6 (0.62) | HDAC3HDAC1HDAC2HDAC6VNN1 | |
| SCHEMBL18742445 | 0.81 | HDAC3 (0.53) | HDAC3HDAC1HDAC2HDAC6VNN1 | |
| SCHEMBL28247610 | 0.81 | HDAC6 (0.61) | HDAC3HDAC1HDAC2HDAC6VNN1 | |
| SCHEMBL19710705 | 0.80 | HDAC6 (0.67) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL24967744 | 0.78 | VNN1 (0.56) | HDAC3HDAC1HDAC2HDAC6VNN1 | |
| SCHEMBL19710840 | 0.76 | VNN1 (0.61) | HDAC3HDAC1HDAC2HDAC6VNN1 | |
| SCHEMBL24968732 | 0.76 | HTR2C (0.48) | HDAC3HDAC1HDAC2HDAC6VNN1 | |
| SCHEMBL24968633 | 0.75 | HDAC6 (0.67) | HDAC3HDAC1HDAC2HDAC6VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362445-B1 | OXADIAZOLE AMINE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2023-01-25 | — | — | EP | disclosed |