Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23374745 | 0.83 | KDM4E (0.43) | KDM4ESMN1; SMN2CHRNB2CHRNA4MEN1 | |
| SCHEMBL18890757 | 0.81 | CARM1 (0.48) | KDM4ESMN1; SMN2MEN1LMNAKMT2A | |
| SCHEMBL27947483 | 0.78 | SMN1; SMN2 (0.50) | KDM4ESMN1; SMN2CHRNB2CHRNA4CYP3A4 | |
| SCHEMBL733206 | 0.77 | CHRNB2 (0.62) | KDM4ESMN1; SMN2CHRNB2CHRNA4CYP3A4 | |
| SCHEMBL30093206 | 0.76 | KDM4E (0.53) | KDM4ESMN1; SMN2CHRNB2CHRNA4CYP3A4 | |
| SCHEMBL21763492 | 0.74 | ADRA2B (0.47) | KDM4ESMN1; SMN2MEN1LMNAKMT2A | |
| SCHEMBL15308555 | 0.73 | KDM4E (0.51) | KDM4ESMN1; SMN2CHRNB2CHRNA4CYP3A4 | |
| SCHEMBL5948692 | 0.73 | TSHR (0.32) | TSHR | |
| SCHEMBL8294943 | 0.72 | CYP3A4 (0.44) | CHRNB2LMNACYP3A4CYP2D6CYP19A1 | |
| Hydrochloric Acid SCHEMBL9638792 | 0.72 | MAPT (0.48) | KDM4ESMN1; SMN2MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |