Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15758311 | 0.93 | KDM4E (0.56) | ALDH1A1HPGDMEN1HTTKMT2A | |
| SCHEMBL4016055 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HPGDMEN1HTTKMT2A | |
| SCHEMBL21728084 | 0.81 | HPGD (0.53) | ALDH1A1HPGDMEN1HTTKMT2A | |
| SCHEMBL23757590 | 0.81 | GAA (0.54) | ALDH1A1MEN1HTTKMT2AMAPK1 | |
| SCHEMBL30144759 | 0.81 | GAA (0.54) | ALDH1A1MEN1HTTKMT2AMAPK1 | |
| SCHEMBL8038343 | 0.81 | KDM4E (0.50) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL2322279 | 0.80 | HPGD (0.59) | ALDH1A1HPGDMEN1HTTKMT2A | |
| SCHEMBL14392489 | 0.80 | HPGD (0.59) | ALDH1A1HPGDMEN1HTTKMT2A | |
| SCHEMBL9491052 | 0.79 | TRPA1 (0.59) | ALDH1A1MEN1KMT2AKDM4EPDE4B | |
| SCHEMBL5210543 | 0.79 | HPGD (0.58) | ALDH1A1HPGDMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |