Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152251 | 1.00 | TAAR1 (0.50) | TAAR1HDAC4MEF2DAPPSHMT2 | |
| SCHEMBL13054791 | 0.85 | SMN1; SMN2 (0.46) | IDO1 | |
| SCHEMBL22288489 | 0.82 | SHMT2 (0.50) | TAAR1HDAC4MEF2DAPPSHMT2 | |
| SCHEMBL31577324 | 0.82 | SHMT2 (0.50) | TAAR1HDAC4MEF2DAPPSHMT2 | |
| SCHEMBL11935975 | 0.79 | SHMT2 (0.57) | TAAR1HDAC4MEF2DSHMT2MAOB | |
| SCHEMBL28119262 | 0.78 | APP (0.52) | TAAR1HDAC4MEF2DAPPRPS6KB1 | |
| SCHEMBL5203429 | 0.75 | SHMT2 (0.56) | HDAC4MEF2DSHMT2IDO1 | |
| SCHEMBL16041691 | 0.75 | APP (0.44) | TAAR1HDAC4MEF2DAPPSHMT2 | |
| SCHEMBL6695675 | 0.74 | MAPT (0.52) | RPS6KB1FFAR1NOS1CCNT1 | |
| SCHEMBL6069372 | 0.73 | CYP1A2 (0.50) | TAAR1RPS6KB1AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |