Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152247 | 1.00 | KDM1A (0.40) | KDM1AKDM1BGAACYP19A1DRD2 | |
| SCHEMBL24969124 | 0.84 | GAA (0.36) | GAACYP19A1MEN1LMNAMAPT | |
| SCHEMBL14840700 | 0.77 | BACE1 (0.32) | KDM1AKDM1BCYP19A1MEN1LMNA | |
| SCHEMBL14840513 | 0.74 | MEN1 (0.39) | GAAMEN1MAPTKMT2A | |
| SCHEMBL24969059 | 0.74 | EGFR (0.42) | RAB9A | |
| SCHEMBL14840478 | 0.73 | MAPT (0.37) | GAACYP19A1DRD2DRD3MEN1 | |
| SCHEMBL5451243 | 0.73 | MEN1 (0.49) | GAACYP19A1MEN1LMNAMAPT | |
| SCHEMBL6436184 | 0.73 | MEN1 (0.49) | GAACYP19A1MEN1LMNAMAPT | |
| SCHEMBL29903416 | 0.73 | MEN1 (0.49) | GAACYP19A1MEN1LMNAMAPT | |
| SCHEMBL24969123 | 0.71 | BRD4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |