Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24969126 | 0.84 | KDM1A (0.40) | GAALMNAMAPTMEN1KMT2A | |
| SCHEMBL30152247 | 0.84 | KDM1A (0.40) | GAALMNAMAPTMEN1KMT2A | |
| SCHEMBL24969059 | 0.74 | EGFR (0.42) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24969521 | 0.73 | MAPT (0.43) | GAANPC1LMNAMAPTMEN1 | |
| SCHEMBL24969123 | 0.71 | BRD4 (0.42) | — | |
| SCHEMBL30152236 | 0.71 | NISCH (0.43) | MAPK14NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL24969071 | 0.71 | NISCH (0.43) | MAPK14NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL24969069 | 0.70 | CYP3A4 (0.48) | NPC1LMNAMAPTCYP19A1ALDH1A1 | |
| SCHEMBL30152309 | 0.70 | CYP3A4 (0.48) | NPC1LMNAMAPTCYP19A1ALDH1A1 | |
| SCHEMBL5451243 | 0.70 | MEN1 (0.49) | GAANPC1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |