Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 14/20 | 0.42 |
| ▸ | ITK | Q08881 | 9/20 | 0.39 |
| ▸ | BTK | Q06187 | 3/20 | 0.39 |
| ▸ | TGM2 | P21980 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24969123 | 0.81 | BRD4 (0.42) | — | |
| SCHEMBL30152193 | 0.81 | BRD4 (0.42) | — | |
| SCHEMBL24969061 | 0.80 | EGFR (0.44) | EGFRBTKTGM2NPC1TP53 | |
| SCHEMBL24969062 | 0.78 | MAOB (0.44) | EGFRITKBTKTGM2 | |
| SCHEMBL30152292 | 0.78 | MAOB (0.44) | EGFRITKBTKTGM2 | |
| SCHEMBL24968466 | 0.77 | CYP19A1 (0.57) | EGFRTGM2 | |
| SCHEMBL24969126 | 0.74 | KDM1A (0.40) | RAB9A | |
| SCHEMBL30152247 | 0.74 | KDM1A (0.40) | RAB9A | |
| SCHEMBL24969124 | 0.74 | GAA (0.36) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24968851 | 0.68 | TGM2 (0.42) | EGFRITKTGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |