SCHEMBL24969156

SCHEMBL24969156

Clc1cccc2sc3cc(-c4ccccc4)ccc3c12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.41
MAPK1 P28482 1/20 0.41
LIMK1 P53667 2/20 0.40
ESR2 Q92731 1/20 0.40
PIK3CA P42336 1/20 0.37
PI4KA P42356 1/20 0.37
PI4KB Q9UBF8 1/20 0.37
SMO Q99835 1/20 0.36
CYP1A2 P05177 1/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.35
HPGD P15428 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
F9 P00740 3/20 0.35
PGR P06401 1/20 0.35
PLAU P00749 1/20 0.35
HSD17B1 P14061 1/20 0.34
DHFR P00374 1/20 0.34
OGG1 O15527 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27282404 1.00 MCL1 (0.41) MCL1MAPK1LIMK1ESR2PIK3CA
SCHEMBL25567689 0.89 CYP2A6 (0.42) MCL1MAPK1LIMK1ALDH1A1MAPT
SCHEMBL22650685 0.87 MAPK1 (0.41) MCL1MAPK1LIMK1ESR2PIK3CA
SCHEMBL31615244 0.87 MAPK1 (0.41) MCL1MAPK1LIMK1ESR2PIK3CA
SCHEMBL25567798 0.87 MAPK1 (0.41) MCL1MAPK1LIMK1ESR2PIK3CA
SCHEMBL25981533 0.87 ADORA2A (0.37) MCL1MAPK1LIMK1ALDH1A1MAPT
SCHEMBL19656415 0.84 MAPK1 (0.35) MCL1MAPK1LIMK1ESR2CYP1A2
SCHEMBL22700523 0.84 MEN1 (0.42) MCL1MAPK1ALDH1A1MAPTHPGD
SCHEMBL21398895 0.82 ALDH1A1 (0.37) MCL1MAPK1LIMK1ALDH1A1MAPT
SCHEMBL19010387 0.82 LIMK1 (0.44) MCL1LIMK1PIK3CAPI4KAPI4KB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024013276-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2024-01-18 WO disclosed
WO-2023003234-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2023-01-26 WO disclosed