SCHEMBL19010387

SCHEMBL19010387

Cc1cccc2sc3cc(-c4ccccc4)ccc3c12

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 8/20 0.44
TNKS2 Q9H2K2 1/20 0.41
PIK3CA P42336 1/20 0.38
PI4KA P42356 1/20 0.38
PI4KB Q9UBF8 1/20 0.38
PLAU P00749 1/20 0.37
MCL1 Q07820 1/20 0.37
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
F9 P00740 3/20 0.36
PIK3CG P48736 1/20 0.35
HSD17B1 P14061 1/20 0.34
HSD17B2 P37059 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23624439 0.87 PLAU (0.36) LIMK1PLAUALDH1A1MAPTHPGD
SCHEMBL19841607 0.87 LIMK1 (0.44) LIMK1TNKS2PIK3CAPI4KAPI4KB
SCHEMBL21742578 0.86 L3MBTL1 (0.42) LIMK1PIK3CAPI4KAPI4KBMCL1
SCHEMBL21742558 0.86 LIMK1 (0.47) LIMK1PIK3CAPI4KAPI4KBPLAU
SCHEMBL23624466 0.83 LIMK1 (0.48) LIMK1ALDH1A1HPGDSMN1; SMN2
SCHEMBL23051245 0.83 LIMK1 (0.39) LIMK1TNKS2PIK3CAPI4KAPI4KB
SCHEMBL13507007 0.82 LIMK1 (0.45) LIMK1TNKS2PIK3CAPI4KAPI4KB
SCHEMBL21742510 0.82 LIMK1 (0.52) LIMK1PIK3CAPI4KAPI4KBALDH1A1
SCHEMBL24969156 0.82 MCL1 (0.41) LIMK1PIK3CAPI4KAPI4KBPLAU
SCHEMBL22450512 0.82 LIMK1 (0.47) LIMK1PIK3CAPI4KAPI4KBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11832513-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2023-11-28 US disclosed
US-11832513-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2023-11-28 US disclosed
US-20230363260-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-09 US disclosed
US-11807654-B2 Organometallic compound, organic light-emitting device including organometallic compound, and diagnostic composition including organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-11-07 US disclosed
US-20230301189-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-21 US disclosed
US-20230301189-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-21 US disclosed
EP-4242286-A2 MATERIALS FOR ELECTRONIC DEVICES Merck Patent GmbH (DE) 2023-09-13 EP disclosed
US-11730053-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-15 US disclosed
US-20230200227-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-06-22 US disclosed
US-20230200227-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-06-22 US disclosed
EP-3670520-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND Samsung Electronics Co., Ltd. (KR) 2020-06-24 EP disclosed
WO-2020032574-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2020-02-13 WO disclosed
WO-2019101719-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-05-31 WO disclosed
EP-3489249-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2019-05-29 EP disclosed
US-20190153008-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-05-23 US disclosed
US-20190036039-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-01-31 US disclosed
US-20180130964-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-10 US disclosed
US-20180130964-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-10 US disclosed
US-9887372-B2 Amine-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-02-06 US disclosed
WO-2017102064-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11832513-B2 Materials for electronic devices PNMT, DDT, COMT LIMK1 2465/4885TNKS2 1570/4885PIK3CA 4028/4885
US-20190036039-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, LEF1, CRY2 LIMK1 448/4885TNKS2 4118/4885PIK3CA 4114/4885
US-20190153008-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, LEF1, POU2F1 LIMK1 318/4885TNKS2 3997/4885PIK3CA 4607/4885
US-20180130964-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING ORGANOMETALLIC COMPOUND ORC3, OCIAD1, LEF1 LIMK1 239/4885TNKS2 4440/4885PIK3CA 3399/4885
US-11807654-B2 Organometallic compound, organic light-emitting device including organometallic compound, and diagnostic composition including organometallic compound L1CAM, FOXM1, MEN1 LIMK1 48/4885TNKS2 4323/4885PIK3CA 4568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.