SCHEMBL24969655

SCHEMBL24969655

Clc1ccc2c(c1)sc1cc(-c3ccccc3)ccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.50
BCKDK O14874 1/20 0.45
MCL1 Q07820 1/20 0.45
RXFP1 Q9HBX9 1/20 0.45
LIMK1 P53667 2/20 0.44
KDM4E B2RXH2 1/20 0.42
PGR P06401 1/20 0.41
PIK3CA P42336 1/20 0.41
PI4KA P42356 1/20 0.41
PI4KB Q9UBF8 1/20 0.41
ESR2 Q92731 2/20 0.40
ALDH1A1 P00352 2/20 0.39
HPGD P15428 2/20 0.39
RAB9A P51151 2/20 0.39
MAPT P10636 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
F9 P00740 2/20 0.38
LMNA P02545 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
DHODH Q02127 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24969675 0.91 KDM4E (0.50) CYP1A2BCKDKMCL1RXFP1LIMK1
SCHEMBL25620852 0.91 KDM4E (0.46) CYP1A2BCKDKMCL1RXFP1LIMK1
SCHEMBL24969654 0.91 KDM4E (0.46) CYP1A2BCKDKMCL1RXFP1LIMK1
SCHEMBL12562737 0.88 LIMK1 (0.51) LIMK1KDM4EPIK3CAPI4KAPI4KB
SCHEMBL10110898 0.88 LIMK1 (0.51) LIMK1KDM4EPIK3CAPI4KAPI4KB
SCHEMBL25567679 0.88 RXFP1 (0.41) CYP1A2BCKDKMCL1RXFP1LIMK1
SCHEMBL24742153 0.87 BCKDK (0.39) CYP1A2BCKDKMCL1RXFP1LIMK1
SCHEMBL30563047 0.85 GPR3 (0.52) CYP1A2MCL1LIMK1KDM4EALDH1A1
SCHEMBL23235920 0.85 GPR3 (0.52) CYP1A2MCL1LIMK1KDM4EALDH1A1
SCHEMBL22227748 0.85 HTT (0.46) CYP1A2BCKDKMCL1RXFP1LIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023003234-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2023-01-26 WO disclosed