SCHEMBL24969759

SCHEMBL24969759

Clc1ccc(-c2cccc3sc4ccc(-c5ccccc5)cc4c23)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.43
KDM4E B2RXH2 2/20 0.41
F9 P00740 1/20 0.40
PIM3 Q86V86 1/20 0.39
CHEK1 O14757 1/20 0.39
WEE1 P30291 1/20 0.39
MAP4K4 O95819 1/20 0.38
LIMK1 P53667 2/20 0.37
CNR1 P21554 2/20 0.37
SLC9A1 P19634 1/20 0.36
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PTPN1 P18031 1/20 0.35
EDNRB P24530 1/20 0.35
EDNRA P25101 1/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24778315 0.93 KDM4E (0.49) CYP1A2KDM4EF9PIM3CHEK1
SCHEMBL22045662 0.90 KDM4E (0.51) CYP1A2KDM4EF9CHEK1WEE1
SCHEMBL24969282 0.89 CYP1A2 (0.43) CYP1A2KDM4EF9MAP4K4LIMK1
SCHEMBL29643200 0.87 EGFR (0.38) CYP1A2KDM4EPIM3MAP4K4LIMK1
SCHEMBL21930661 0.87 EGFR (0.38) CYP1A2KDM4EPIM3MAP4K4LIMK1
SCHEMBL20391688 0.85 EGFR (0.37) CYP1A2KDM4EPIM3LIMK1CNR1
SCHEMBL23770307 0.85 KDM4E (0.44) CYP1A2KDM4EF9LIMK1POLB
SCHEMBL19803044 0.84 PIM3 (0.41) KDM4EF9PIM3CHEK1WEE1
SCHEMBL25568103 0.84 F9 (0.40) CYP1A2KDM4EF9MAP4K4LIMK1
SCHEMBL25567636 0.84 KDM4E (0.49) KDM4EF9CHEK1WEE1LIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023003234-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2023-01-26 WO disclosed