SCHEMBL23770307

SCHEMBL23770307

Clc1ccc(-c2cccc3sc4ccccc4c23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
GPR3 P46089 1/20 0.43
ALOX5 P09917 1/20 0.39
GABRA1 P14867 1/20 0.38
GABRA5 P31644 1/20 0.38
PTGS2 P35354 2/20 0.38
CYP1A2 P05177 2/20 0.38
PTGS1 P23219 1/20 0.38
BRDT Q58F21 1/20 0.36
CYP1A1 P04798 1/20 0.36
CYP1B1 Q16678 1/20 0.36
LIMK1 P53667 1/20 0.36
LOXL2 Q9Y4K0 1/20 0.36
F9 P00740 1/20 0.36
MEN1 O00255 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
DUSP3 P51452 1/20 0.36
BLM P54132 1/20 0.36
PTPN5 P54829 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20696037 0.91 GPR3 (0.52) KDM4EGPR3ALOX5CYP1A2BRDT
SCHEMBL25748042 0.88 KDM4E (0.41) KDM4EGPR3ALOX5GABRA1GABRA5
SCHEMBL28965024 0.86 GPR3 (0.46) GPR3ALOX5BRDTLIMK1F9
SCHEMBL2474182 0.85 GPR3 (0.50) GPR3ALOX5BRDTLIMK1F9
SCHEMBL30021871 0.85 GPR3 (0.50) GPR3ALOX5BRDTLIMK1F9
SCHEMBL24969282 0.85 CYP1A2 (0.43) KDM4ECYP1A2CYP1A1CYP1B1LIMK1
SCHEMBL24969759 0.85 CYP1A2 (0.43) KDM4ECYP1A2LIMK1F9MEN1
Bromide SCHEMBL27902456 0.84 GPR3 (0.48) GPR3ALOX5BRDTLIMK1F9
SCHEMBL21795107 0.84 KDM4E (0.43) KDM4EGPR3ALOX5CYP1A2BRDT
SCHEMBL24778315 0.83 KDM4E (0.49) KDM4EALOX5CYP1A2LIMK1F9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230123170-A1 COMPOUND, MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE COMPOUND IDEMITSU KOSAN CO.,LTD. (JP) 2023-04-20 US disclosed
US-20220109108-A1 LIGHT EMITTING DEVICE AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2022-04-07 US disclosed
CN-114249744-A Light emitting device and polycyclic compound used therefor 三星显示有限公司 2022-03-29 CN disclosed
WO-2021162122-A1 COMPOUND, MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2021-08-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230123170-A1 COMPOUND, MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE COMPOUND L1CAM, LEF1, CCNL2 KDM4E 1947/4885GPR3 2904/4885ALOX5 1852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.