Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.50 |
| ▸ | FAAH | O00519 | 11/20 | 0.46 |
| ▸ | PHGDH | O43175 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20566954 | 0.89 | MGLL (0.64) | MGLLFAAH | |
| SCHEMBL30302074 | 0.89 | MGLL (0.64) | MGLLFAAH | |
| SCHEMBL22041699 | 0.88 | MGLL (0.49) | MGLLFAAH | |
| SCHEMBL30302087 | 0.86 | MGLL (0.51) | MGLLFAAH | |
| SCHEMBL20567100 | 0.86 | MGLL (0.51) | MGLLFAAH | |
| SCHEMBL20570833 | 0.83 | MGLL (0.43) | MGLLFAAHKDR | |
| SCHEMBL20567025 | 0.80 | GPR119 (0.48) | — | |
| SCHEMBL25487236 | 0.79 | MGLL (0.66) | MGLLFAAH | |
| SCHEMBL25829823 | 0.79 | MGLL (0.57) | MGLLFAAHKDR | |
| SCHEMBL25830289 | 0.77 | MGLL (0.69) | MGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630744-B1 | PYRAZOLE MAGL INHIBITORS | H LUNDBECK AS (DK) | 2023-01-25 | — | — | EP | disclosed |