Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421479 | 0.88 | GABRG2 (0.40) | KMT2AMEN1HPGDGABRG2GABRB3 | |
| SCHEMBL22263387 | 0.81 | GABRG2 (0.36) | KMT2AMEN1HPGDGABRG2GABRB3 | |
| SCHEMBL28788197 | 0.79 | KMT2A (0.37) | KMT2AMEN1HPGDNPC1MAPT | |
| SCHEMBL20920373 | 0.78 | KMT2A (0.53) | KMT2AMEN1HPGDNPC1MAPT | |
| SCHEMBL22190961 | 0.76 | HPGDS (0.39) | GABRG2GABRB3GABRA5MAPTHPGDS | |
| SCHEMBL17633162 | 0.76 | CYP4F2 (0.39) | KMT2AMEN1HPGDMAPTBCHE | |
| SCHEMBL28155365 | 0.75 | BCHE (0.37) | KMT2AMEN1HPGDNPC1MAPT | |
| SCHEMBL28074789 | 0.75 | SCN4A (0.38) | HPGDGABRG2GABRB3GABRA5MAPT | |
| SCHEMBL25234455 | 0.73 | BCHE (0.33) | KMT2AMEN1BCHEABCB1FAAH | |
| SCHEMBL17361380 | 0.73 | CYP4F2 (0.42) | KMT2AMEN1HPGDMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4198024-A1 | PYRAZOLE MAGL INHIBITORS | H. Lundbeck A/S (DK) | 2023-06-21 | — | — | EP | disclosed |
| EP-3630744-B1 | PYRAZOLE MAGL INHIBITORS | H LUNDBECK AS (DK) | 2023-01-25 | — | — | EP | disclosed |