SCHEMBL24969834

SCHEMBL24969834

O=C(O)c1ccn(C(=O)N2C[C@H]3CC(OCc4ccccc4Cl)C[C@H]3C2)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 16/20 1.00
FAAH O00519 9/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25640026 1.00 MGLL (1.00) MGLLFAAH
SCHEMBL20920412 1.00 MGLL (1.00) MGLLFAAH
SCHEMBL20920370 1.00 MGLL (1.00) MGLLFAAH
SCHEMBL24969914 1.00 MGLL (1.00) MGLLFAAH
SCHEMBL25829837 0.91 MGLL (0.84) MGLLFAAH
SCHEMBL25829895 0.91 MGLL (0.84) MGLLFAAH
SCHEMBL20570601 0.88 MGLL (0.78) MGLLFAAH
SCHEMBL20920378 0.87 MGLL (0.77) MGLLFAAH
SCHEMBL24969832 0.87 MGLL (0.77) MGLLFAAH
SCHEMBL24971322 0.87 MGLL (0.77) MGLLFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4198024-A1 PYRAZOLE MAGL INHIBITORS H. Lundbeck A/S (DK) 2023-06-21 EP disclosed
EP-3630744-B1 PYRAZOLE MAGL INHIBITORS H LUNDBECK AS (DK) 2023-01-25 EP disclosed