Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.54 |
| ▸ | MGLL | Q99685 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20566497 | 0.89 | FAAH (0.56) | FAAHMGLLALDH1A1KMT2A | |
| SCHEMBL30302100 | 0.87 | FAAH (0.69) | FAAHMGLLALDH1A1KDM4E | |
| SCHEMBL20566972 | 0.87 | FAAH (0.69) | FAAHMGLLALDH1A1KDM4E | |
| SCHEMBL20566975 | 0.84 | FAAH (0.66) | FAAHMGLL | |
| SCHEMBL20566887 | 0.83 | MGLL (0.63) | FAAHMGLL | |
| SCHEMBL30302111 | 0.83 | MGLL (0.63) | FAAHMGLL | |
| SCHEMBL25487231 | 0.83 | FAAH (0.50) | FAAHMGLL | |
| SCHEMBL20920371 | 0.79 | FAAH (0.49) | FAAHMGLL | |
| SCHEMBL25487151 | 0.79 | FAAH (0.63) | FAAHMGLLALDH1A1 | |
| SCHEMBL20567312 | 0.79 | FAAH (0.54) | FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630744-B1 | PYRAZOLE MAGL INHIBITORS | H LUNDBECK AS (DK) | 2023-01-25 | — | — | EP | disclosed |