Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2503228 | 1.00 | GAA (0.53) | GAAFFAR1POLBTAS1R3TAS1R1 | |
| SCHEMBL3658199 | 0.90 | GAA (0.57) | GAAFFAR1POLBTAS1R3TAS1R1 | |
| SCHEMBL3657093 | 0.90 | GAA (0.57) | GAAFFAR1POLBTAS1R3TAS1R1 | |
| SCHEMBL2497911 | 0.85 | GAA (0.52) | GAAFFAR1POLBTAS1R3TAS1R1 | |
| SCHEMBL2499134 | 0.85 | GAA (0.52) | GAAFFAR1POLBTAS1R3TAS1R1 | |
| SCHEMBL2498025 | 0.81 | TRPA1 (0.46) | GAAFFAR1ALDH1A1 | |
| SCHEMBL2502889 | 0.81 | TRPA1 (0.46) | GAAFFAR1ALDH1A1 | |
| SCHEMBL3873634 | 0.78 | GAA (0.47) | GAAFFAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11225638 | 0.78 | FFAR1 (0.56) | GAAFFAR1POLBTAS1R3TAS1R1 | |
| SCHEMBL2503226 | 0.77 | TNF (0.44) | GAAFFAR1TAS1R3TAS1R1TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030354-B2 | 2-(5,5-Dimethylcyclopent-1-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; metabolic disorders such as type II diabetes | AMGEN INC. (US) | 2011-10-04 | — | — | US | disclosed |