SCHEMBL24970384

SCHEMBL24970384

O=C(O)c1ccn(C(=O)N2C[C@H]3CC(Oc4cccc(-c5ccccc5)c4)C[C@H]3C2)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FAAH O00519 9/20 1.00
MGLL Q99685 14/20 0.89

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20920416 1.00 FAAH (1.00) FAAHMGLL
SCHEMBL20920431 1.00 FAAH (1.00) FAAHMGLL
SCHEMBL30420395 1.00 FAAH (1.00) FAAHMGLL
SCHEMBL20920450 0.94 MGLL (1.00) FAAHMGLL
SCHEMBL30420839 0.94 MGLL (1.00) FAAHMGLL
SCHEMBL25830104 0.92 FAAH (0.85) FAAHMGLL
SCHEMBL25830035 0.92 FAAH (0.85) FAAHMGLL
SCHEMBL20920396 0.91 FAAH (0.84) FAAHMGLL
SCHEMBL30302075 0.91 FAAH (0.84) FAAHMGLL
SCHEMBL24971346 0.91 FAAH (0.84) FAAHMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3630744-B1 PYRAZOLE MAGL INHIBITORS H LUNDBECK AS (DK) 2023-01-25 EP disclosed