SCHEMBL24970404

SCHEMBL24970404

Cc1cc(CN2CCN(C(=O)n3ccc(C(=O)O)n3)CC2)ccc1-c1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 7/20 0.75
FAAH O00519 12/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25643226 0.86 MGLL (0.57) MGLLFAAH
SCHEMBL20566561 0.86 MGLL (1.00) MGLLFAAH
SCHEMBL30420338 0.86 MGLL (1.00) MGLLFAAH
SCHEMBL24235958 0.86 MGLL (1.00) MGLLFAAH
SCHEMBL20566559 0.86 MGLL (1.00) MGLLFAAH
SCHEMBL24970134 0.85 FAAH (0.72) MGLLFAAH
SCHEMBL20571359 0.83 FAAH (0.71) MGLLFAAH
SCHEMBL25487216 0.82 FAAH (0.61) MGLLFAAH
SCHEMBL20566347 0.81 FAAH (1.00) MGLLFAAH
SCHEMBL25830237 0.79 MGLL (0.88) MGLLFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3630744-B1 PYRAZOLE MAGL INHIBITORS H LUNDBECK AS (DK) 2023-01-25 EP disclosed