Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.51 |
| ▸ | MGLL | Q99685 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30302105 | 0.89 | FAAH (0.66) | FAAHMGLL | |
| SCHEMBL20566964 | 0.89 | FAAH (0.66) | FAAHMGLL | |
| SCHEMBL21271341 | 0.86 | FAAH (0.46) | FAAHMGLL | |
| SCHEMBL20567002 | 0.86 | FAAH (0.54) | FAAHMGLL | |
| SCHEMBL30302067 | 0.86 | FAAH (0.54) | FAAHMGLL | |
| SCHEMBL20571297 | 0.83 | MGLL (0.45) | FAAHMGLLCYP2D6ABHD6 | |
| SCHEMBL31483872 | 0.80 | MGLL (0.49) | MGLLCYP2D6ABHD6 | |
| SCHEMBL20567724 | 0.80 | MGLL (0.49) | MGLLCYP2D6ABHD6 | |
| SCHEMBL24970070 | 0.79 | FAAH (0.78) | FAAHMGLLCYP2D6ABHD6 | |
| SCHEMBL25487182 | 0.79 | FAAH (0.58) | FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006893-A1 | COMPOUNDS FOR THE TREATMENT OF PAIN, IN PARTICULAR NEUROPATHIC PAIN, AND/OR OTHER DISEASES OR DISORDERS THAT ARE ASSOCIATED WITH AT2R AND/OR AT2R MEDIATED SIGNALING | CONFO THERAPEUTICS N.V. (BE) | 2023-02-02 | — | — | WO | disclosed |
| EP-3630744-B1 | PYRAZOLE MAGL INHIBITORS | H LUNDBECK AS (DK) | 2023-01-25 | — | — | EP | disclosed |