SCHEMBL24970514

SCHEMBL24970514

CN(Cc1cccc(-c2ccccc2)c1)C1C[C@@H]2CN(C(=O)n3ccc(C(=O)O)n3)C[C@@H]2C1

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FAAH O00519 9/20 0.61
MGLL Q99685 13/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20920414 1.00 FAAH (0.61) FAAHMGLL
SCHEMBL20920464 1.00 FAAH (0.61) FAAHMGLL
SCHEMBL30420266 1.00 FAAH (0.61) FAAHMGLL
SCHEMBL25830338 0.94 MGLL (0.55) FAAHMGLL
SCHEMBL25830103 0.94 MGLL (0.55) FAAHMGLL
SCHEMBL25642868 0.87 MGLL (0.48) FAAHMGLL
SCHEMBL20920410 0.81 MGLL (0.81) FAAHMGLL
SCHEMBL20920466 0.81 FAAH (0.63) FAAHMGLL
SCHEMBL30420421 0.81 MGLL (0.75) FAAHMGLL
SCHEMBL20920469 0.81 MGLL (0.75) FAAHMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3630744-B1 PYRAZOLE MAGL INHIBITORS H LUNDBECK AS (DK) 2023-01-25 EP disclosed