SCHEMBL24970531

SCHEMBL24970531

O=C(O)c1ccn(C(=O)N2CC3CN(Cc4ccc(Cl)c(-c5nccs5)c4)CC3C2)n1

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 9/20 0.71
FAAH O00519 13/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20567180 1.00 MGLL (0.71) MGLLFAAH
SCHEMBL25830362 0.92 MGLL (0.61) MGLLFAAH
SCHEMBL20567708 0.89 MGLL (0.80) MGLLFAAH
SCHEMBL20920492 0.85 FAAH (0.61) MGLLFAAH
SCHEMBL30420369 0.85 FAAH (0.61) MGLLFAAH
SCHEMBL20567189 0.83 MGLL (0.65) MGLLFAAH
SCHEMBL24235997 0.83 MGLL (0.65) MGLLFAAH
SCHEMBL20567305 0.83 MGLL (1.00) MGLLFAAH
SCHEMBL20567190 0.83 MGLL (0.65) MGLLFAAH
SCHEMBL25830289 0.81 MGLL (0.69) MGLLFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4198024-A1 PYRAZOLE MAGL INHIBITORS H. Lundbeck A/S (DK) 2023-06-21 EP disclosed
EP-3630744-B1 PYRAZOLE MAGL INHIBITORS H LUNDBECK AS (DK) 2023-01-25 EP disclosed