SCHEMBL24970562

SCHEMBL24970562

O=C(O)c1ccn(C(=O)N2CCC(OCc3cccc(Oc4ccc(Cl)cc4)c3)CC2)n1

nearest known ligand 0.77

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 10/20 0.77
FAAH O00519 15/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30302115 0.90 FAAH (0.74) MGLLFAAH
SCHEMBL20566731 0.90 FAAH (0.74) MGLLFAAH
SCHEMBL30420809 0.88 FAAH (0.74) MGLLFAAH
SCHEMBL20920406 0.88 FAAH (0.74) MGLLFAAH
SCHEMBL20566273 0.87 MGLL (1.00) MGLLFAAH
SCHEMBL30420855 0.87 MGLL (1.00) MGLLFAAH
SCHEMBL22042098 0.87 MGLL (1.00) MGLLFAAH
SCHEMBL20566978 0.87 MGLL (1.00) MGLLFAAH
SCHEMBL20566976 0.87 MGLL (1.00) MGLLFAAH
SCHEMBL30421109 0.87 MGLL (1.00) MGLLFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4198024-A1 PYRAZOLE MAGL INHIBITORS H. Lundbeck A/S (DK) 2023-06-21 EP disclosed
EP-3630744-B1 PYRAZOLE MAGL INHIBITORS H LUNDBECK AS (DK) 2023-01-25 EP disclosed