Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | EIF4E | P06730 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2495875 | 0.86 | HSD17B10 (0.46) | HSD17B10AHRPTGER1PTGER3PTGER2 | |
| SCHEMBL2497952 | 0.83 | NPC1 (0.42) | PTGS2EIF4EAKR1C3AKR1C2TSHR | |
| SCHEMBL2493681 | 0.79 | ALDH1A1 (0.41) | PTGS2PTGS1EIF4EAKR1C3AKR1C2 | |
| SCHEMBL27756441 | 0.78 | MAPT (0.39) | TSHRALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL28427977 | 0.78 | AHR (0.56) | HSD17B10AHREIF4EAKR1C3AKR1C2 | |
| SCHEMBL2234399 | 0.77 | ALDH1A1 (0.53) | CYP3A4AKR1C3AKR1C2ALDH1A1NPC1 | |
| SCHEMBL2500102 | 0.76 | TSHR (0.40) | TSHRALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL28010867 | 0.76 | ALDH1A1 (0.41) | CYP3A4TSHRALDH1A1NPC1RAB9A | |
| SCHEMBL2501051 | 0.76 | HSD17B10 (0.42) | HSD17B10AHREIF4ECYP3A4TSHR | |
| SCHEMBL31511380 | 0.76 | PIN1 (0.42) | ALDH1A1NPC1RAB9AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030527-B2 | Process for preparing substituted biphenyls | BASF SE (DE) | 2011-10-04 | — | — | US | disclosed |
| US-20100256418-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | SMIDT SEBASTIAN PEER | 2010-10-07 | — | — | US | disclosed |
| US-7709684-B2 | Process for preparing substituted biphenyls | BASF SE (DE) | 2010-05-04 | — | — | US | disclosed |
| EP-2029519-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2009-03-04 | — | — | EP | disclosed |
| US-20090005597-A1 | Process for Preparing Substituted Biphenyls | BASF SE (DE) | 2009-01-01 | — | — | US | disclosed |
| WO-2007138089-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2007-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256418-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | CBR3, HRH3, CBR1 | HSD17B10 850/4885AHR 12/4885PTGS2 4153/4885 |
| US-20090005597-A1 | Process for Preparing Substituted Biphenyls | CBR3, HRH3, CBR1 | HSD17B10 563/4885AHR 24/4885PTGS2 4693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.