Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 13/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24971005 | 0.85 | MEN1 (0.46) | MEN1KMT2AP2RY12SMN1; SMN2ALDH1A1 | |
| SCHEMBL24970110 | 0.84 | KMT2A (0.43) | MEN1KMT2AP2RY12SMN1; SMN2ALDH1A1 | |
| SCHEMBL24971021 | 0.81 | KMT2A (0.41) | MEN1KMT2AP2RY12SMN1; SMN2ALDH1A1 | |
| SCHEMBL24969707 | 0.78 | P2RY12 (0.40) | MEN1KMT2AP2RY12SMN1; SMN2ALDH1A1 | |
| SCHEMBL24971003 | 0.77 | MEN1 (0.40) | MEN1KMT2AP2RY12SMN1; SMN2ALDH1A1 | |
| SCHEMBL24970949 | 0.72 | TRPV1 (0.40) | — | |
| SCHEMBL899500 | 0.70 | SMN1; SMN2 (0.48) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL14018906 | 0.69 | MEN1 (0.46) | MEN1KMT2AP2RY12SMN1; SMN2ALDH1A1 | |
| SCHEMBL899444 | 0.69 | MEN1 (0.54) | MEN1KMT2AP2RY12SMN1; SMN2ALDH1A1 | |
| SCHEMBL30223144 | 0.69 | MEN1 (0.54) | MEN1KMT2AP2RY12SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002011-A1 | GRAM-NEGATIVE BACTERIA EFFLUX PUMP INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-01-26 | — | — | WO | disclosed |