Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.40 |
| ▸ | HTR3B | O95264 | 4/20 | 0.39 |
| ▸ | HTR3A | P46098 | 4/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30903372 | 0.79 | POLB (0.55) | TRPV1HTR3BHTR3ATRPA1HTR3E | |
| SCHEMBL24970948 | 0.79 | POLB (0.55) | TRPV1HTR3BHTR3ATRPA1HTR3E | |
| SCHEMBL24969735 | 0.75 | KDM4E (0.52) | HTR3BHTR3AHRH4 | |
| SCHEMBL24970163 | 0.75 | TRPV1 (0.34) | TRPV1TRPA1KCNH2TRPM8CNR2 | |
| SCHEMBL24970855 | 0.74 | ALDH1A1 (0.43) | HTR1AHRH4 | |
| SCHEMBL24971005 | 0.74 | MEN1 (0.46) | TRPV1PHGDHSMO | |
| SCHEMBL24969955 | 0.73 | HTR2C (0.52) | HTR3BHTR3AHTR3EHTR3DHTR3C | |
| SCHEMBL31142978 | 0.73 | HTR2C (0.52) | HTR3BHTR3AHTR3EHTR3DHTR3C | |
| SCHEMBL24970110 | 0.73 | KMT2A (0.43) | TRPV1PHGDH | |
| SCHEMBL24969924 | 0.72 | TRPV1 (0.31) | TRPV1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002011-A1 | GRAM-NEGATIVE BACTERIA EFFLUX PUMP INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-01-26 | — | — | WO | disclosed |