SCHEMBL899444

SCHEMBL899444

CC(C)(C)OC(=O)N1CCN(c2ncc(CO)cc2Cl)CC1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
NR1H2 P55055 1/20 0.48
NR1H3 Q13133 1/20 0.48
GPR119 Q8TDV5 4/20 0.47
CNR1 P21554 1/20 0.44
CNR2 P34972 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
MAPT P10636 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
ALDH1A1 P00352 1/20 0.44
POLB P06746 1/20 0.44
KIT P10721 2/20 0.44
CKS1B P61024 1/20 0.43
SKP1 P63208 1/20 0.43
SKP2 Q13309 1/20 0.43
SUV39H2 Q9H5I1 2/20 0.43
HTT P42858 1/20 0.43
TSHR P16473 1/20 0.43
P2RY12 Q9H244 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30223144 1.00 MEN1 (0.54) MEN1KMT2ANR1H2NR1H3GPR119
SCHEMBL19212337 0.88 MEN1 (0.51) MEN1KMT2ANR1H2NR1H3GPR119
SCHEMBL29268346 0.87 MEN1 (0.50) MEN1KMT2ANR1H2NR1H3GPR119
SCHEMBL25209396 0.86 GPR119 (0.47) MEN1KMT2ANR1H2NR1H3GPR119
SCHEMBL2366192 0.85 MEN1 (0.55) MEN1KMT2ANR1H2NR1H3GPR119
SCHEMBL30223154 0.85 GPR119 (0.48) MEN1KMT2ANR1H2NR1H3GPR119
SCHEMBL2366069 0.84 MEN1 (0.57) MEN1KMT2ANR1H2NR1H3GPR119
SCHEMBL2419702 0.84 MEN1 (0.47) MEN1KMT2AGPR119KITCKS1B
SCHEMBL22322349 0.84 MEN1 (0.54) MEN1KMT2ANR1H2NR1H3GPR119
SCHEMBL4286978 0.84 MEN1 (0.54) MEN1KMT2ANR1H2NR1H3GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119528804-A 2- { [2- (Phenoxymethyl) pyridin-5-yl ] oxy } ethanamine derivatives and related compounds as pest control agents, for example, for protecting plants 发现号收购集团 2025-02-28 CN disclosed
CN-119285538-A 2- { [2- (Phenoxymethyl) pyridin-5-yl ] oxy } ethanamine derivatives and related compounds as pest control agents, for example, for protecting plants 发现号收购集团 2025-01-10 CN disclosed
CN-118076585-A Gram negative bacteria efflux pump inhibitors 国家医疗保健研究所 2024-05-24 CN disclosed
US-20240109860-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2024-04-04 US disclosed
US-11827616-B2 Heterocyclic compounds as pesticides DISCOVERY PURCHASER CORPORATION (US) 2023-11-28 US disclosed
WO-2023002011-A1 GRAM-NEGATIVE BACTERIA EFFLUX PUMP INHIBITORS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2023-01-26 WO disclosed
EP-3619196-B1 2-{[2-(PHENYLOXYMETHYL)PYRIDIN-5-YL]OXY}-ETHANAMIN-DERIVATIVES AND RELATED COMPOUNDS AS PESTICIDES E.G. FOR CROP PROTECTION BAYER CROPSCIENCE AG (DE) 2022-03-30 EP disclosed
CN-110869349-A 2- { [2- (phenoxymethyl) pyridin-5-yl ] oxy } ethanamine derivatives and related compounds as pest control agents, e.g. for protecting plants 拜耳作物科学股份公司 2020-03-06 CN disclosed
US-20200062729-A1 NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES DISCOVERY PURCHASER CORPORATION 2020-02-27 US disclosed
EP-2621920-A1 NOVEL PIPERAZINE ANALOGS WITH SUBSTITUTED HETEROARYL GROUPS AS BROAD-SPECTRUM INFLUENZA ANTIVIRALS Bristol-Myers Squibb Company (US) 2013-08-07 EP disclosed
US-20120245176-A1 NOVEL PIPERAZINE ANALOGS WITH SUBSTITUTED HETEROARYL GROUPS AS BROAD-SPECTRUM INFLUENZA ANTIVIRALS BRISTOL-MYERS SQUIBB COMPANY 2012-09-27 US disclosed
WO-2012044531-A1 NOVEL PIPERAZINE ANALOGS WITH SUBSTITUTED HETEROARYL GROUPS AS BROAD-SPECTRUM INFLUENZA ANTIVIRALS BRISTOL-MYERS SQUIBB COMPANY (US) 2012-04-05 WO disclosed
US-20090203667-A1 PENTADIENAMIDE DERIVATIVES KYOWA HAKKO KIRIN CO., LTD. (JP) 2009-08-13 US disclosed
CN-101489989-A Pentadiene amide derivative KYOWA HAKKO KIRIN CO LTD (JP) 2009-07-22 CN disclosed
EP-2050734-A1 PENTADIENAMIDE DERIVATIVE Kyowa Hakko Kirin Co., Ltd. (JP) 2009-04-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120245176-A1 NOVEL PIPERAZINE ANALOGS WITH SUBSTITUTED HETEROARYL GROUPS AS BROAD-SPECTRUM INFLUENZA ANTIVIRALS ZC3HAV1, ZC3HAV1L, BAZ2A MEN1 3660/4885KMT2A 548/4885NR1H2 244/4885
US-11827616-B2 Heterocyclic compounds as pesticides DDT, CHRM1, ACHE MEN1 724/4885KMT2A 1690/4885NR1H2 1815/4885
US-20090203667-A1 PENTADIENAMIDE DERIVATIVES PRMT1, REN, NGLY1 MEN1 291/4885KMT2A 772/4885NR1H2 3488/4885
US-20240109860-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES DDT, CHRM1, ACHE MEN1 724/4885KMT2A 1690/4885NR1H2 1815/4885
US-20200062729-A1 NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES CHRM1, DDT, ACHE MEN1 951/4885KMT2A 1757/4885NR1H2 1860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.