Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 3/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | DDO | Q99489 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31143052 | 1.00 | MAPT (0.49) | MAPTDAOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3360987 | 0.84 | DAO (0.61) | MAPTDAODDO | |
| SCHEMBL24970979 | 0.76 | DAO (0.65) | DAOHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL29955876 | 0.75 | MAPT (0.46) | MAPTDAOALDH1A1CSNK2A2CSNK2B | |
| SCHEMBL3605104 | 0.74 | HPGD (0.53) | MAPTDAOHSD17B10KDM4EALDH1A1 | |
| SCHEMBL28881409 | 0.70 | DAO (0.64) | MAPTDAOHSD17B10KDM4EALDH1A1 | |
| SCHEMBL30235048 | 0.70 | DAO (0.38) | MAPTDAOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL25604921 | 0.70 | DAO (0.38) | MAPTDAOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL4048527 | 0.68 | CDK1 (0.64) | MAPTHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL25418850 | 0.68 | TDP1 (0.37) | DAOGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002011-A1 | GRAM-NEGATIVE BACTERIA EFFLUX PUMP INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-01-26 | — | — | WO | disclosed |