Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 17/20 | 0.61 |
| ▸ | DDO | Q99489 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24970965 | 0.84 | MAPT (0.49) | DAODDOMAPT | |
| SCHEMBL31143052 | 0.84 | MAPT (0.49) | DAODDOMAPT | |
| SCHEMBL3364081 | 0.83 | DAO (0.65) | DAODDO | |
| SCHEMBL3363037 | 0.80 | DAO (0.61) | DAODDO | |
| SCHEMBL3435254 | 0.80 | DAO (0.61) | DAODDO | |
| SCHEMBL16767858 | 0.76 | DAO (1.00) | DAODDO | |
| SCHEMBL3361211 | 0.73 | DAO (0.53) | DAODDOMAPT | |
| SCHEMBL3605104 | 0.73 | HPGD (0.53) | DAOMAPT | |
| SCHEMBL3363264 | 0.73 | DAO (0.61) | DAODDO | |
| SCHEMBL3418547 | 0.73 | DAO (0.61) | DAODDOMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |