Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNF4 | P78317 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.46 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702218 | 0.95 | RNF4 (0.51) | RNF4TSHRLMNAALDH1A1BCL2A1 | |
| SCHEMBL17628547 | 0.90 | RNF4 (0.58) | RNF4TSHRALDH1A1MAPTBCL2A1 | |
| SCHEMBL27654625 | 0.82 | ALDH1A1 (0.60) | TSHRHPGDLTB4R2ALDH1A1NPC1 | |
| SCHEMBL15984777 | 0.81 | SMN1; SMN2 (0.62) | RNF4TSHRHPGDALDH1A1MAPT | |
| SCHEMBL5454456 | 0.79 | HTT (0.51) | RNF4TSHRHPGDALDH1A1NPC1 | |
| SCHEMBL14577947 | 0.79 | TSHR (0.49) | RNF4TSHRHPGDALDH1A1MAPT | |
| SCHEMBL11875667 | 0.79 | SMN1; SMN2 (0.47) | RNF4TSHRHPGDALDH1A1NPC1 | |
| SCHEMBL7044788 | 0.78 | TSHR (0.51) | RNF4TSHRLMNAHPGDALDH1A1 | |
| SCHEMBL6801988 | 0.78 | TSHR (0.58) | TSHRLMNAHPGDMCHR1ALDH1A1 | |
| SCHEMBL545097 | 0.78 | TSHR (0.45) | RNF4TSHRLMNAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401275-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | Respiratorius AB (SE) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097410-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | RESPIRATORIUS AB (SE) | 2010-09-02 | — | — | WO | disclosed |