Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702218 | 0.82 | RNF4 (0.51) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL15984777 | 0.82 | SMN1; SMN2 (0.62) | TSHRALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL5454456 | 0.81 | HTT (0.51) | TSHRALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL14577947 | 0.81 | TSHR (0.49) | TSHRALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL11875667 | 0.81 | SMN1; SMN2 (0.47) | TSHRALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL11214776 | 0.80 | CES2 (0.55) | TSHRHPGDKDM4ELMNACES2 | |
| SCHEMBL1844719 | 0.80 | OPRM1 (0.67) | TSHRALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL6801166 | 0.80 | ESR1 (0.58) | TSHRALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6800782 | 0.80 | STS (0.56) | — | |
| SCHEMBL1926257 | 0.80 | TRPM8 (0.64) | TSHRALDH1A1HPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |