Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25754219 | 1.00 | RNASE1 (0.35) | RNASE1TOP2A | |
| SCHEMBL24971684 | 1.00 | RNASE1 (0.35) | RNASE1TOP2A | |
| SCHEMBL22327411 | 0.89 | RNASE1 (0.35) | RNASE1TOP2A | |
| SCHEMBL22327415 | 0.89 | RNASE1 (0.35) | RNASE1TOP2A | |
| SCHEMBL26068492 | 0.89 | RNASE1 (0.35) | RNASE1TOP2A | |
| SCHEMBL24971683 | 0.89 | RNASE1 (0.36) | RNASE1TOP2A | |
| SCHEMBL28609124 | 0.89 | RNASE1 (0.37) | RNASE1TOP2A | |
| SCHEMBL21814692 | 0.87 | RNASE1 (0.37) | RNASE1TOP2A | |
| SCHEMBL20810626 | 0.87 | RNASE1 (0.37) | RNASE1TOP2A | |
| SCHEMBL18214116 | 0.87 | RNASE1 (0.37) | RNASE1TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203083-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-06-29 | — | — | US | disclosed |
| US-20230203083-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-06-29 | — | — | US | disclosed |
| US-20230028359-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230028359-A1 | NUCLEOTIDE ANALOGUES | ITPA, POLB, NUDT1 | RNASE1 179/4885TOP2A 66/4885 |
| US-20230203083-A1 | NUCLEOTIDE ANALOGUES | ITPA, POLB, NUDT1 | RNASE1 179/4885TOP2A 66/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.