Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
| ▸ | POLD1 | P28340 | 1/20 | 0.44 |
| ▸ | DTYMK | P23919 | 4/20 | 0.39 |
| ▸ | TK1 | P04183 | 3/20 | 0.39 |
| ▸ | POLG | P54098 | 1/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22327429 | 0.92 | POLB (0.42) | POLBPOLA1POLD1DTYMKTK1 | |
| SCHEMBL22326990 | 0.92 | POLB (0.42) | POLBPOLA1POLD1DTYMKTK1 | |
| SCHEMBL25753578 | 0.89 | POLB (0.40) | POLBPOLA1POLD1DTYMKTK1 | |
| SCHEMBL25753928 | 0.89 | POLB (0.40) | POLBPOLA1POLD1DTYMKTK1 | |
| SCHEMBL25763826 | 0.86 | POLB (0.42) | POLBPOLA1POLD1DTYMKTK1 | |
| SCHEMBL26167872 | 0.85 | FUT5 (0.43) | POLBPOLA1POLD1DTYMKTK1 | |
| SCHEMBL22327100 | 0.85 | POLB (0.53) | POLBPOLA1POLD1DTYMKTK1 | |
| SCHEMBL22326991 | 0.85 | POLB (0.53) | POLBPOLA1POLD1DTYMKTK1 | |
| SCHEMBL22327212 | 0.85 | POLB (0.53) | POLBPOLA1POLD1DTYMKTK1 | |
| SCHEMBL22327091 | 0.84 | FUT5 (0.41) | POLBPOLA1POLD1DTYMKTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203083-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-06-29 | — | — | US | disclosed |
| US-20230028359-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230028359-A1 | NUCLEOTIDE ANALOGUES | ITPA, POLB, NUDT1 | POLB 2/4885POLA1 37/4885POLD1 127/4885 |
| US-20230203083-A1 | NUCLEOTIDE ANALOGUES | ITPA, POLB, NUDT1 | POLB 2/4885POLA1 37/4885POLD1 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.