SCHEMBL2497372

SCHEMBL2497372

C=C(C)c1ccc([Si](CC)(OC(C)(C)C)c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2495006 0.87 ALDH1A1 (0.36) TSHR
SCHEMBL706547 0.84 MAPK1 (0.32)
SCHEMBL2501155 0.81 PAX8 (0.33) TSHR
SCHEMBL2504307 0.81 PAX8 (0.33) TSHR
SCHEMBL2500237 0.79 NPSR1 (0.30)
SCHEMBL2497634 0.78 ALDH1A1 (0.38) TSHR
SCHEMBL2496923 0.77 MEN1 (0.33)
SCHEMBL9436623 0.74 HPGD (0.31) TSHR
SCHEMBL10646504 0.71 ESR1 (0.39)
SCHEMBL705588 0.71 MAPK1 (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8497334-B2 Conjugated diene polymer, conjugated diene polymer composition, and method for producing conjugated diene polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-30 US disclosed
US-20110245407-A1 CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-10-06 US disclosed