Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24974117 | 0.92 | PGR (0.33) | PGRALDH1A1MAPTMEN1GAA | |
| SCHEMBL24974119 | 0.89 | PGR (0.33) | PGRALDH1A1MAPTITGB2ICAM1 | |
| SCHEMBL24974118 | 0.89 | PGR (0.35) | PGRALDH1A1MAPTMEN1GAA | |
| SCHEMBL24974225 | 0.89 | ITGB2 (0.33) | PGRALDH1A1MAPTMEN1GAA | |
| SCHEMBL22063753 | 0.88 | ITGB2 (0.34) | PGRALDH1A1MAPTMEN1GAA | |
| SCHEMBL24974123 | 0.88 | PGR (0.33) | PGRMAPTITGB2ICAM1ITGAL | |
| SCHEMBL19318169 | 0.85 | ITGB2 (0.31) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL24974679 | 0.83 | HDAC6 (0.31) | ITGB2ICAM1ITGAL | |
| SCHEMBL24974079 | 0.83 | MEN1 (0.32) | MAPTMEN1KMT2AITGB2ICAM1 | |
| SCHEMBL19318118 | 0.83 | ITGB2 (0.31) | ALDH1A1MAPTMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11572378-B2 | Heterocyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572378-B2 | Heterocyclic compound and organic light-emitting device including the same | CYP1A1, CRY1, CYP1B1 | PGR 1471/4885ALDH1A1 4/4885MAPT 1799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.