Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | UCHL5 | Q9Y5K5 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24974733 | 0.87 | TACR1 (0.35) | TACR1NAMPTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL24974366 | 0.86 | KDM4E (0.42) | TACR1NAMPTPOLBHDAC3HDAC1 | |
| SCHEMBL24974537 | 0.77 | SMN1; SMN2 (0.33) | TACR1SMN1; SMN2ALDH1A1POLBTSHR | |
| SCHEMBL24974736 | 0.76 | TACR1 (0.51) | TACR1NAMPTPOLBHDAC3HDAC1 | |
| SCHEMBL24974639 | 0.75 | SMN1; SMN2 (0.41) | TACR1NAMPTSMN1; SMN2ALDH1A1HDAC3 | |
| SCHEMBL24974548 | 0.74 | KMT2A (0.37) | TACR1NAMPTPOLBKDM4EKDR | |
| SCHEMBL21150858 | 0.73 | NAMPT (0.36) | NAMPTHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL21150845 | 0.72 | NAMPT (0.34) | TACR1NAMPTHDAC3HDAC1HDAC2 | |
| SCHEMBL21151259 | 0.72 | NAMPT (0.34) | TACR1NAMPTALDH1A1HDAC3HDAC1 | |
| SCHEMBL21151783 | 0.71 | NAMPT (0.33) | TACR1NAMPTSMN1; SMN2HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11572370-B2 | CD16A binding agents and uses thereof | BIOHAVEN THERAPEUTICS LTD. (US) | 2023-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572370-B2 | CD16A binding agents and uses thereof | FCGR1A, FCGR2A, FCGR3B | TACR1 76/4885NAMPT 1356/4885SMN1; SMN2 3020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.