SCHEMBL24974746

SCHEMBL24974746

CCCOCCOCCOCCn1cc(-c2cnc(NC(=O)N3CCC4(CC3)NC(=O)N(c3ccccc3)C4=O)nc2)nn1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ NPY5R Q15761 10/20 0.37
▸ NAMPT P43490 4/20 0.36
▸ EGLN1 Q9GZT9 2/20 0.36
▸ EGLN3 Q9H6Z9 2/20 0.36
▸ ITGB3 P05106 1/20 0.35
▸ ITGA2B P08514 1/20 0.35
▸ FABP7 O15540 1/20 0.35
▸ HDAC3 O15379 1/20 0.33
▸ HDAC1 Q13547 1/20 0.33
▸ HDAC2 Q92769 1/20 0.33
▸ HDAC6 Q9UBN7 1/20 0.33
▸ KDM6B O15054 1/20 0.33
▸ KDM5C P41229 1/20 0.33
▸ KDM2A Q9Y2K7 1/20 0.33
▸ KDM3A Q9Y4C1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24974366 0.79 KDM4E (0.42) NAMPTEGLN1EGLN3ITGB3ITGA2B
SCHEMBL24974548 0.79 KMT2A (0.37) NAMPTFABP7
SCHEMBL24974772 0.79 AKT1 (0.40) NAMPTFABP7
SCHEMBL24974553 0.77 HRH4 (0.36) FABP7
SCHEMBL24974788 0.76 AKT1 (0.37) NAMPTFABP7
SCHEMBL24974747 0.74 DYRK3 (0.36) EGLN1FABP7
SCHEMBL24974609 0.74 FABP7 (0.40) EGLN1EGLN3FABP7
SCHEMBL21150858 0.73 NAMPT (0.36) NPY5RNAMPTFABP7HDAC3HDAC1
SCHEMBL24974642 0.72 TACR1 (0.39) NPY5RNAMPTFABP7
SCHEMBL21152134 0.72 NPY5R (0.43) NPY5REGLN1EGLN3ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11572370-B2 CD16A binding agents and uses thereof BIOHAVEN THERAPEUTICS LTD. (US) 2023-02-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11572370-B2 CD16A binding agents and uses thereof FCGR1A, FCGR2A, FCGR3B NPY5R 2528/4885NAMPT 1356/4885EGLN1 4635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback