Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CHKA | P35790 | 2/20 | 0.36 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428496 | 0.86 | HRH3 (0.38) | HRH3KMT2ACHKATRPV6ACHE | |
| SCHEMBL24977045 | 0.78 | HRH3 (0.45) | HRH3TSHRGRM2ALDH1A1 | |
| SCHEMBL31428722 | 0.78 | HRH3 (0.45) | HRH3TSHRGRM2ALDH1A1 | |
| SCHEMBL31428855 | 0.77 | KMT2A (0.47) | KMT2ACHKAMEN1GRM2KDM4E | |
| SCHEMBL24975435 | 0.76 | HRH3 (0.38) | HRH3 | |
| SCHEMBL24975806 | 0.75 | CHKA (0.38) | KMT2ACHKAACHEPKMMEN1 | |
| SCHEMBL24976089 | 0.72 | HSD11B1 (0.36) | KDM4E | |
| SCHEMBL31428837 | 0.68 | HRH3 (0.45) | HRH3KMT2ACHKATRPV6ACHE | |
| SCHEMBL38659590 | 0.68 | KDM4E (0.58) | KMT2ATRPV6MEN1KDM4EALDH1A1 | |
| SCHEMBL12130365 | 0.67 | CCR1 (0.42) | KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |