Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | F10 | P00742 | 3/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428540 | 0.90 | HTR2A (0.40) | HSD11B1SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL31428473 | 0.83 | MAPT (0.37) | HSD11B1SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL31429027 | 0.79 | F2R (0.34) | HSD11B1SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL31428890 | 0.79 | F2R (0.34) | HSD11B1SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL31429018 | 0.79 | HTR2A (0.42) | HSD11B1SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL24977051 | 0.76 | CETP (0.33) | HSD11B1KDM4ENPC1RAB9AKDM1A | |
| SCHEMBL24975442 | 0.74 | ALDH1A1 (0.35) | HSD11B1SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL31428751 | 0.74 | ALDH1A1 (0.35) | HSD11B1SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL24975434 | 0.72 | HRH3 (0.38) | KDM4E | |
| SCHEMBL30163473 | 0.71 | NR1H4 (0.38) | HSD11B1SLC6A2SLC6A4SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |