Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.31 |
| ▸ | PTPRC | P08575 | 2/20 | 0.31 |
| ▸ | LIPC | P11150 | 2/20 | 0.30 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428946 | 0.91 | MAPT (0.39) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL31428707 | 0.89 | ALDH1A1 (0.38) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL31428638 | 0.89 | ALDH1A1 (0.44) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL31428665 | 0.87 | HTT (0.37) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL24977060 | 0.87 | HTT (0.37) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL31428814 | 0.87 | MAPK1 (0.43) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL30163521 | 0.85 | ALDH1A1 (0.45) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL31428573 | 0.85 | HPGD (0.37) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL31428962 | 0.84 | PDCD1 (0.42) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL24976130 | 0.84 | PDCD1 (0.42) | ALDH1A1MEN1KMT2APDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |