Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 7/20 | 0.44 |
| ▸ | ACACA | Q13085 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428695 | 1.00 | GBA1 (0.45) | GBA1ALDH1A1MAPTACACBACACA | |
| SCHEMBL31428908 | 0.94 | ALDH1A1 (0.43) | GBA1ALDH1A1MAPTACACBACACA | |
| SCHEMBL30163482 | 0.93 | ALDH1A1 (0.44) | ALDH1A1MAPTACACBACACAHPGD | |
| SCHEMBL31428632 | 0.92 | HPGD (0.43) | GBA1ALDH1A1MAPTACACBACACA | |
| SCHEMBL31428999 | 0.87 | ACACB (0.42) | ALDH1A1MAPTACACBACACAHPGD | |
| SCHEMBL24975488 | 0.87 | ACACB (0.42) | ALDH1A1MAPTACACBACACAHPGD | |
| SCHEMBL31428640 | 0.87 | ACACB (0.45) | ALDH1A1MAPTACACBACACAHPGD | |
| SCHEMBL31428513 | 0.84 | PDCD1 (0.53) | ALDH1A1MAPTHPGDPOLB | |
| SCHEMBL31428608 | 0.81 | ACACB (0.43) | ALDH1A1MAPTACACBACACAHPGD | |
| SCHEMBL24977053 | 0.80 | ACACB (0.44) | ALDH1A1MAPTACACBACACAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |