Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.42 |
| ▸ | ACACA | Q13085 | 4/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428999 | 1.00 | ACACB (0.42) | ACACBACACALRRK2LMNASMN1; SMN2 | |
| SCHEMBL30163482 | 0.90 | ALDH1A1 (0.44) | ACACBACACALRRK2LMNASMN1; SMN2 | |
| SCHEMBL31428968 | 0.87 | ACACB (0.41) | ACACBACACALRRK2LMNAHTR2C | |
| SCHEMBL31428908 | 0.87 | ALDH1A1 (0.43) | ACACBACACAMGLLALDH1A1MAPT | |
| SCHEMBL31428695 | 0.87 | GBA1 (0.45) | ACACBACACAMGLLALDH1A1MAPT | |
| SCHEMBL24975480 | 0.87 | GBA1 (0.45) | ACACBACACAMGLLALDH1A1MAPT | |
| SCHEMBL31428699 | 0.86 | HTR2C (0.53) | HTR2CKDM4EALDH1A1HPGD | |
| SCHEMBL31428632 | 0.86 | HPGD (0.43) | ACACBACACALMNAMGLLALDH1A1 | |
| SCHEMBL31428701 | 0.80 | ALDH1A1 (0.35) | ACACBACACALRRK2LMNASMN1; SMN2 | |
| SCHEMBL31428585 | 0.78 | LMNA (0.52) | LMNASMN1; SMN2NCF1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |