Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23975626 | 0.69 | EPHX1 (0.31) | EPHX1 | |
| SCHEMBL21148654 | 0.65 | EPHX1 (0.37) | EPHX1 | |
| SCHEMBL7597619 | 0.65 | EPHX1 (0.38) | EPHX1ALDH1A1TSHR | |
| SCHEMBL5954723 | 0.64 | LPAR1 (0.33) | EPHX1ALDH1A1TSHR | |
| SCHEMBL9750773 | 0.64 | OPRM1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL8965926 | 0.64 | TSHR (0.31) | TSHR | |
| SCHEMBL22624028 | 0.63 | TSHR (0.42) | EPHX1TSHR | |
| SCHEMBL24943233 | 0.63 | TSHR (0.42) | EPHX1TSHR | |
| SCHEMBL21159161 | 0.63 | TSHR (0.42) | EPHX1TSHR | |
| SCHEMBL18430943 | 0.63 | TSHR (0.42) | EPHX1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230037284-A9 | COMBINATION THERAPY OF PEPTIDOMIMETIC MACROCYCLES | AILERON THERAPEUTICS, INC. | 2023-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230037284-A9 | COMBINATION THERAPY OF PEPTIDOMIMETIC MACROCYCLES | BID, FLT3, GRPR | EPHX1 4656/4885ALDH1A1 4722/4885TSHR 802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.