Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.31 |
| ▸ | FDPS | P14324 | 8/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 5/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21665733 | 0.76 | CYP4F2 (0.34) | TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL518098 | 0.74 | TSHR (0.39) | LPAR1LPAR3TSHRTHRBSMPD1 | |
| SCHEMBL517884 | 0.72 | TSHR (0.44) | LPAR1LPAR3TSHRTHRBSMPD1 | |
| SCHEMBL2397669 | 0.72 | TSHR (0.44) | LPAR1LPAR3TSHRTHRBSMPD1 | |
| SCHEMBL517658 | 0.72 | TSHR (0.44) | LPAR1LPAR3TSHRTHRBSMPD1 | |
| SCHEMBL7597619 | 0.72 | EPHX1 (0.38) | TSHRTHRBFDPSGGPS1ALDH1A1 | |
| SCHEMBL518405 | 0.72 | TSHR (0.44) | LPAR1LPAR3TSHRTHRBSMPD1 | |
| SCHEMBL1891306 | 0.72 | TSHR (0.44) | LPAR1LPAR3TSHRTHRBSMPD1 | |
| SCHEMBL28544233 | 0.71 | SMPD1 (0.32) | SMPD1 | |
| SCHEMBL23473217 | 0.70 | TSHR (0.35) | LPAR1LPAR3TSHRTHRBFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692096-A1 | HYDROXYLAMINE DERIVATIVES | Newron Pharmaceuticals S.p.A. (IT) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005058800-A1 | HYDROXYLAMINE DERIVATIVES | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-06-30 | — | — | WO | disclosed |