Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17038141 | 0.84 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2CYP2C19KDM4E | |
| SCHEMBL24992674 | 0.78 | CA1 (0.58) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL11173803 | 0.78 | MAPT (0.56) | RAB9ANPC1SMN1; SMN2CYP2A6KDM4E | |
| SCHEMBL31428993 | 0.77 | NPC1 (0.44) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3113690 | 0.76 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2CYP2D6CYP3A4 | |
| SCHEMBL14273336 | 0.75 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2CYP3A4CYP2C19 | |
| SCHEMBL11180711 | 0.75 | NPC1 (0.51) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL31738413 | 0.75 | CA1 (0.57) | CYP2D6CYP3A4CYP2C19CA2CA1 | |
| SCHEMBL31019504 | 0.75 | GFER (0.56) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28367183 | 0.75 | GFER (0.56) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |