Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24975786 | 0.84 | RAB9A (0.44) | RAB9ASMN1; SMN2NPC1MAPTKDM4E | |
| SCHEMBL11173803 | 0.81 | MAPT (0.56) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL15356380 | 0.81 | SMN1; SMN2 (0.56) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL17038139 | 0.81 | RAB9A (0.56) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL31428993 | 0.80 | NPC1 (0.44) | RAB9ASMN1; SMN2NPC1MAPTKMT2A | |
| SCHEMBL17038138 | 0.76 | SMN1; SMN2 (0.58) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL7601340 | 0.76 | RAB9A (0.67) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL10271447 | 0.76 | SMN1; SMN2 (0.67) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL2756575 | 0.76 | RAB9A (0.67) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL16155802 | 0.75 | ATP4A (0.55) | RAB9ASMN1; SMN2NPC1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150239878-A1 | Novel Compounds for Imaging Tau Proteins That Accumulate In Brain | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239878-A1 | Novel Compounds for Imaging Tau Proteins That Accumulate In Brain | MAPT, FABP7, HTT | RAB9A 1040/4885SMN1; SMN2 2701/4885NPC1 1994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.