Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428465 | 0.93 | GRM2 (0.39) | SLC6A2SLC6A4SLC6A3GRM2KCNH2 | |
| SCHEMBL31428746 | 0.92 | GRM2 (0.35) | SLC6A2SLC6A4SLC6A3GRM2HSD11B1 | |
| SCHEMBL24975804 | 0.92 | GRM2 (0.35) | SLC6A2SLC6A4SLC6A3GRM2HSD11B1 | |
| SCHEMBL31428830 | 0.90 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3GRM2KCNH2 | |
| SCHEMBL24975810 | 0.89 | GRM2 (0.35) | SLC6A2SLC6A4SLC6A3GRM2KCNH2 | |
| SCHEMBL31428558 | 0.89 | GRM2 (0.35) | SLC6A2SLC6A4SLC6A3GRM2KCNH2 | |
| SCHEMBL31428920 | 0.85 | GRM2 (0.38) | GRM2KCNH2 | |
| SCHEMBL24975439 | 0.85 | IRAK1 (0.36) | GRM2CCNCCDK8 | |
| SCHEMBL31428821 | 0.85 | IRAK1 (0.36) | GRM2CCNCCDK8 | |
| SCHEMBL24975799 | 0.84 | REN (0.33) | SLC6A2SLC6A4SLC6A3GRM2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |