Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CCNC | P24863 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428448 | 1.00 | MAPT (0.51) | MAPTTP53NPC1RAB9AMEN1 | |
| SCHEMBL24975803 | 0.90 | NPC1 (0.56) | MAPTTP53NPC1RAB9AMEN1 | |
| SCHEMBL31428675 | 0.90 | NPC1 (0.56) | MAPTTP53NPC1RAB9AMEN1 | |
| SCHEMBL31428851 | 0.87 | NPC1 (0.54) | MAPTTP53NPC1RAB9AMEN1 | |
| SCHEMBL24975644 | 0.87 | NPC1 (0.54) | MAPTTP53NPC1RAB9AMEN1 | |
| SCHEMBL24976116 | 0.86 | CTRC (0.50) | MAPTTP53NPC1RAB9AMEN1 | |
| SCHEMBL31428985 | 0.86 | CTRC (0.50) | MAPTTP53NPC1RAB9AMEN1 | |
| SCHEMBL24975465 | 0.85 | ABCG2 (0.43) | MAPTTP53NPC1MEN1KMT2A | |
| SCHEMBL31428407 | 0.85 | ABCG2 (0.43) | MAPTTP53NPC1MEN1KMT2A | |
| SCHEMBL31428599 | 0.84 | NPC1 (0.55) | MAPTTP53NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |