Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | IP6K1 | Q92551 | 4/20 | 0.44 |
| ▸ | IP6K3 | Q96PC2 | 4/20 | 0.44 |
| ▸ | IP6K2 | Q9UHH9 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24976116 | 1.00 | CTRC (0.50) | CTRCDHODHIP6K1IP6K3IP6K2 | |
| SCHEMBL31428992 | 0.88 | IP6K1 (0.53) | DHODHIP6K1IP6K3IP6K2ALDH1A1 | |
| SCHEMBL31428448 | 0.86 | MAPT (0.51) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL24975796 | 0.86 | MAPT (0.51) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL31429025 | 0.85 | IP6K1 (0.55) | IP6K1IP6K3IP6K2ALDH1A1KDM4E | |
| SCHEMBL24975611 | 0.85 | IP6K1 (0.55) | IP6K1IP6K3IP6K2ALDH1A1KDM4E | |
| SCHEMBL24975465 | 0.85 | ABCG2 (0.43) | CTRCDHODHALDH1A1KDM4EGAA | |
| SCHEMBL31428407 | 0.85 | ABCG2 (0.43) | CTRCDHODHALDH1A1KDM4EGAA | |
| SCHEMBL31428983 | 0.81 | ALDH1A1 (0.49) | IP6K1IP6K3IP6K2ALDH1A1KDM4E | |
| SCHEMBL24975642 | 0.81 | ABL1 (0.52) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | CTRC 3010/4885DHODH 3234/4885IP6K1 1834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.